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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKA
All Species:
28.18
Human Site:
S283
Identified Species:
41.33
UniProt:
O14965
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14965
NP_003591.2
403
45809
S283
G
W
S
V
H
A
P
S
S
R
R
T
T
L
C
Chimpanzee
Pan troglodytes
XP_525364
403
45791
S283
G
W
S
V
H
A
P
S
S
R
R
T
T
L
C
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
S355
G
W
S
V
H
T
P
S
L
R
R
K
T
M
C
Dog
Lupus familis
XP_853397
405
45606
S284
G
W
S
V
H
A
P
S
S
R
R
T
T
L
C
Cat
Felis silvestris
Mouse
Mus musculus
P97477
395
44754
S274
G
W
S
V
H
A
P
S
S
R
R
T
T
M
C
Rat
Rattus norvegicus
P59241
397
44856
S276
G
W
S
V
H
A
P
S
S
R
R
T
T
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
L188
P
S
S
R
R
T
T
L
C
G
T
L
D
Y
L
Chicken
Gallus gallus
XP_425725
409
46456
I286
G
S
N
G
E
L
K
I
A
D
F
G
W
S
V
Frog
Xenopus laevis
Q91819
408
46443
S290
G
W
S
V
H
A
P
S
S
R
R
T
T
L
C
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
R205
S
V
H
A
P
S
L
R
R
R
T
M
C
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
G213
N
K
R
R
T
L
C
G
T
L
D
Y
L
P
P
Honey Bee
Apis mellifera
XP_395732
327
37711
V212
V
A
D
F
G
W
S
V
H
A
P
S
S
R
R
Nematode Worm
Caenorhab. elegans
O01427
305
34731
M190
R
Q
T
M
C
G
T
M
D
Y
L
P
P
E
M
Sea Urchin
Strong. purpuratus
XP_001181990
278
32048
T163
A
P
S
S
R
R
N
T
L
C
G
T
M
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
T167
D
F
G
W
S
V
H
T
F
N
R
R
R
T
M
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
N252
D
F
G
W
S
I
I
N
P
P
E
N
R
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
47.7
89.8
N.A.
82.6
83.6
N.A.
65.5
73.1
65.9
53.3
N.A.
38.4
53
46.6
50.6
Protein Similarity:
100
100
62.2
93
N.A.
86.8
87.3
N.A.
70.2
82.8
77.2
65.7
N.A.
57.8
67
56.3
60
P-Site Identity:
100
100
73.3
100
N.A.
93.3
100
N.A.
6.6
6.6
100
6.6
N.A.
0
0
0
13.3
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
6.6
20
100
13.3
N.A.
6.6
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.3
57.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
38
0
0
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
7
0
7
7
0
0
7
0
44
% C
% Asp:
13
0
7
0
0
0
0
0
7
7
7
0
7
7
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
7
0
0
7
0
% E
% Phe:
0
13
0
7
0
0
0
0
7
0
7
0
0
0
0
% F
% Gly:
50
0
13
7
7
7
0
7
0
7
7
7
0
7
0
% G
% His:
0
0
7
0
44
0
7
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
7
7
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
7
% K
% Leu:
0
0
0
0
0
13
7
7
13
7
7
7
7
32
7
% L
% Met:
0
0
0
7
0
0
0
7
0
0
0
7
7
13
13
% M
% Asn:
7
0
7
0
0
0
7
7
0
7
0
7
0
0
0
% N
% Pro:
7
7
0
0
7
0
44
0
7
7
7
7
7
7
7
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
7
13
13
7
0
7
7
50
50
7
13
13
7
% R
% Ser:
7
13
57
7
13
7
7
44
38
0
0
7
7
7
0
% S
% Thr:
0
0
7
0
7
13
13
13
7
0
13
44
44
7
7
% T
% Val:
7
7
0
44
0
7
0
7
0
0
0
0
0
0
7
% V
% Trp:
0
44
0
13
0
7
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _